Kinetics of angiotensin -1 converting enzyme inhibition and antioxidative properties of Azadirachta indica seed protein hydrolysates

Angiotensin Converting Enzyme in Sarcoidosis

Role of Tissue Angiotensin-Converting Enzyme Inhibition

Background Chronic treatment with high doses of angiotensin-converting enzyme (ACE) inhibitors prolongs survival after myocardial infarction. Since the plasma reninangiotensin system (RAS) is not consistently activated in the chronic phase after myocardial infarction, the beneficial effects of ACE inhibition have been attributed, in part, to inhibition of an activated tissue RAS. However, a rel...

Effects of Chronic Angiotensin Converting Enzyme Inhibition

Background. Previous studies have shown that global left ventricular function is depressed after myocardial infarction. However, little is known about the effects of myocardial infarction on contractility and the passive-elastic properties of residual myocardium. Methods and Results. We evaluated isometric function and passive myocardial stiffness in isolated, noninfarcted left ventricular papi...

Respiratory effects of angiotensin converting enzyme inhibition.

Angiotensin converting enzyme (ACE) inhibitors have been available for the treatment of hypertension and heart failure for several years. This class of drugs is generally well accepted by the patient (1), but an unusual, infrequent, and troublesome side-effect, cough, has become apparent. This article reviews this side-effect and also the possibility of other respiratory effects of ACE inhibition.

Kinetics of the inhibition of renin and angiotensin I-converting enzyme by cod (Gadus morhua) protein hydrolysates and their antihypertensive effects in spontaneously hypertensive rats

BACKGROUND Cod muscle has a balanced protein profile that contains potentially bioactive amino acid sequences. However, there is limited information on release of these peptides from the parent proteins and their ability to modulate mammalian blood pressure. OBJECTIVE The aim of this study was to generate cod antihypertensive peptides with potent in vitro inhibitory effects against angiotensi...